Tammy LoCascio

Tammy LoCascio

Senior EVP, COO

First Horizon

Tammy LoCascio is Senior Executive Vice President and Chief Operating Officer for First Horizon Corporation. LoCascio is responsible for technology, operations, data and business transformation functions as well as many of the company’s counter-cyclical and national businesses (FHN Financial, Mortgage Warehouse Lending, Correspondent Banking, Franchise Finance and Mortgage).

Prior to this role, LoCascio served as the Senior Executive Vice President and Chief Human Resources Officer since the merger with IBERIABANK. From 2013-2020, she also served as Executive Vice President and Director of Retail Banking and then consumer banking, responsible for the strategic direction and support of retail banking, private client, wealth management, small business, mortgage and consumer loan delivery and the contact centers. LoCascio has also previously held senior leadership roles at Regions and National City Bank.

LoCascio has received noteworthy accolades such as the Woman of Impact by the Memphis American Heart Association, as well as the American Banker Most Powerful Women in Banking Teams award in 2022 and 2024 and Most Powerful Women in Banking Individual award in 2024. She was celebrated as a Super Woman in Business in 2018 by the Memphis Business Journal.

LoCascio is active throughout Memphis and the West Tennessee community. She currently serves on the Greater Memphis Chamber of Commerce as an executive committee member and Chairman’s Circle participant. She is also on the executive committees of the Boys & Girls Club of Greater Memphis, Memphis Riverparks Partnership and the Mid-South Minority Business Continuum. LoCascio also joined the board of directors of Jack Henry & Associates in 2024. 

LoCascio holds a Bachelor of Science degree in Business Administration-Marketing from the University of Florida.

Featured Sessions

Wednesday, October 22, 2025
12:05 pm
Roundtable: Fraud and Cybersecurity

The widespread usage of artificial intelligence (AI) in committing fraud is being countered by financial institutions’ growing reliance on AI and advanced analytics for fraud detection, mitigation and prevention. Increasingly, executives are turning to machine-learning models and behavioral biometrics for real-time detection of fraud. The tough balancing act they face: How to balance speed, accuracy and customer experience with sophisticated guardrails to prevent fraud before it happens. The roundtable discussion will focus on the usage of AI to commit and prevent fraud, strategies being employed to identify fraud patterns and stop them before they occur, and how to model governance, transparency and regulatory expectations for the usage of AI in fraud prevention.